What is the disadvantage of cryogenic freezer?

Cryogenic freezers are powerful tools for preserving and storing materials at extremely low temperatures. However, like any technology, they also have some disadvantages that users should be aware of. In this blog, we will explore some of the disadvantages of cryogenic freezers.

High cost

Cryogenic freezers can be expensive to purchase and maintain. The specialized equipment required to achieve and maintain extremely low temperatures can be costly, and the ongoing cost of cryogenic gases such as liquid nitrogen or liquid helium can add up over time. Additionally, the energy required to operate cryogenic freezers can be significant, contributing to higher utility costs.

Safety hazards

Working with cryogenic freezers requires specialized training and safety equipment. The extremely low temperatures can be dangerous if not handled properly, and contact with cryogenic gases can cause serious injury or even death. In addition, the gases used in cryogenic freezers can displace oxygen in the air, creating a hazard in poorly ventilated areas.

Potential for thermal shock

When samples are removed from a cryogenic freezer and exposed to room temperature, rapid changes in temperature can cause damage to the material. This can lead to the loss of samples or compromise the integrity of the material. To avoid this, samples should be allowed to warm up gradually before being used or transferred to another location.

Limited storage capacity

Cryogenic freezers are typically used for the storage of small samples or materials due to their limited storage capacity. While larger cryogenic freezers are available, they can be expensive and may require specialized equipment to move and transport.

Maintenance requirements

Cryogenic freezers require regular maintenance to ensure their proper operation. This includes tasks such as replacing the insulation, cleaning the cooling system, and monitoring the temperature and pressure of the system. Failure to perform regular maintenance can result in decreased efficiency, increased energy costs, and even damage to the freezer.

Environmental impact

The production and transportation of cryogenic gases such as liquid nitrogen and liquid helium can have an environmental impact. The gases are typically produced through energy-intensive processes, and their transportation can contribute to greenhouse gas emissions.


While cryogenic freezers offer many advantages, they also have some disadvantages that users should be aware of. These include high costs, safety hazards, potential for thermal shock, limited storage capacity, maintenance requirements, and environmental impact. To minimize these disadvantages, users should follow proper safety procedures, perform regular maintenance, and consider alternative storage methods where appropriate.